In old age, hormonal changes play a significant role in the aging process, impacting various aspects of health and well-being. Declining levels of hormones such as estrogen, testosterone, growth hormone, and thyroid hormones contribute to age-related changes in metabolism, muscle mass, bone density, cognitive function, and skin elasticity. Anti-aging therapies targeting hormonal imbalances aim to restore or optimize hormone levels to mitigate the effects of aging. Hormone replacement therapy (HRT), including estrogen and testosterone supplementation, can help alleviate symptoms associated with hormonal decline, such as hot flashes, fatigue, and muscle weakness. Additionally, growth hormone therapy may improve muscle mass, bone density, and overall vitality in older adults.